Purpose

To find whether synergy exists between IP6 and PG490 drug concentration combinations in specific cancer cell lines.
Home Conclusions Project Information Printable Version
 

 

 
Inositol Hexaphosphate
IP6 is found in grain and inhibits cancer cell proliferation.
Triptolide
PG490 is found in a Chinese mushroom and induces cell death.

Synergy
Multiple drugs working together to produce a more effective result.

 

What Is Cancer?

Cancer cells are created as cells in a part of the body grow out of control. Although there are various types of cancer, all types develop through the uncontrollable growth of abnormal cells.

In the body, normal cells go through a cycle (grow, divide, then die) in a repetitive fashion. In the early stages of growth in a human, cells divide at a fast rate, until the person becomes an adult, at which time the cells divide only to replace worn-out cells or dead ones.

Since the abnormal cancer cells divide at an uncontrollable rate, they outlive normal cells in the body, and instead of dying, they continue to divide and form new abnormal cells.

Cancer cells are also capable to travel to other places of the body, where they start growing and dividing once more. This process is called metastasis, and it occurs when cancer cells get into the bloodstream or lymph vessels of the body.

Cancer cells come to being when there is damage to someone’s DNA. Usually when the DNA coding is damaged, the body is able to fix it, but in the case of cancer cells, the body does not repair the damaged DNA, and cancer cells form. The damage to the DNA can be easily caused by the exposure to something in the environment, such as smoking. These damaged DNA can be inherited, and thus allowing people to inherit cancer.

When cancer cells multiply, they usually form tumors. However, there are types of cancer, such as leukemia, do not form tumors, as it travels around the body in the blood system. In the body, not all tumors are cancerous. Benign (noncancerous) tumors do not spread to other parts of the body, and are usually not life-threatening.

The various types of cancer can behave in different ways. For example, different cancers grow at different rates, and respond to treatment differently. Thus, different types of cancer require different types of treatment.

In today’s world, cancer is one of the leading causes of death. Right now, there are millions of people who are living with cancer, or have had cancer in the past. There are high risks of developing cancer, but this can be reduced by changing a person’s lifestyles, such as quiting smoking, or eating a better diet. If cancer is diagnosed, the sooner treatment begins, there are high chances of living for many more years.

 

copyright © 2004, Chris Cheung, Colin Fung, Aaron Chow